Radiolabeled magnetic nanoparticles. To improve the efficacy of targeted diagnosis and .

Radiolabeled magnetic nanoparticles. Abstract Nowadays, emerging radiolabeled nanosystems are revolutionizing medicine in terms of diagnostics, treatment, and theranostics. Multifunctional nanoparticles harboring various functions including targeting, imaging, therapy, and etc have been intensively studied aiming to overcome limitations associated with conventional cancer diagnosis and therapy. Radiolabeled nanoparticles bearing intrinsic properties have gained great interest in multimodality tumor imaging over the past decade. Graves ⊥ , Shreya Goel § , Jonathan W. In this study, magnetic Jun 12, 2023 · The biological behavior of 99m Tc and radiolabeled magnetic solid lipid nanoparticles loaded with azathioprine (99m Tc-AZA-SLMNP) was investigated in vitro and in vivo. These magnetic nanoparticles are a potential vehicle for magnetically induced target aggregation in living animals. Feb 27, 2023 · A convergence of these disciplines has emerged more recently with the advent of nanotechnology-aided radiopharmaceuticals. This work focuses on synthesizing of radiolabeled iron oxide magnetic nanoparticles as a promising dual modality bioprobe (SPECT/MR) for bone imaging. Jul 10, 2018 · In this study, magnetic multimodal nanoparticles with potential applications in magnetic- and nuclear-medicine imaging, magnetic resonance imaging, hyperthermia, and theranostic (therapeutic and diagnostic), applications were prepared by coating iron oxide nanoparticles with silica (core–shell), functionalizing with aminopropyltriethoxy silane and coupling with diethylenetriamine pentaacetic Jul 7, 2025 · Breakthroughs in nanotechnology applications in nuclear medicine hold the potential for improved diagnostic and treatment alternatives. Multimodal imaging combines functional and morphological information from different modalities, which, singularly, cannot provide a comprehensive pathophysiological overview. This review discusses the potential applications of molecular imaging in cancer diagnosis, the utilization of nanotechnology-based radiolabeled materials in multimodal imaging and theranostic Aim: The aim of this study was to develop a dual-modality positron emission tomography/magnetic resonance (PET/MR) imaging probe by radiolabeling gadolinium-containing AGuIX derivatives with the positron-emitter Gallium-68 (68Ga). Radiolabeled magnetic nanoparticles (MNPs), particularly superparamagnetic iron oxide nanoparticles (SPIONs), have gained significant attention in the field of cancer theranostics due to their potential in targeted therapy and molecular imaging. Oct 13, 2017 · Radiolabeled, Antibody-Conjugated Manganese Oxide Nanoparticles for Tumor Vasculature Targeted Positron Emission Tomography and Magnetic Resonance Imaging Yonghua Zhan †‡ , Sixiang Shi †§ , Emily B. Besides surface functionalization, amino acid coating also provided favourable particle size. The advances in nanotechnology are directed towards the development of new theranostic agents based on magnetic nanoparticles that can be used for both cancer detection and treatment. Inorganic nanoparticles Abstract Radiolabeled magnetic nanoparticles (MNPs), particularly superparamagnetic iron oxide nanoparticles (SPIONs), have gained significant attention in the field of cancer theranostics due to their potential in targeted therapy and molecular imaging. Apr 10, 2019 · Nowadays, nanoparticles (NPs) have attracted much attention in biomedical imaging due to their unique magnetic and optical characteristics. Molecular imaging exploits multimodal Jan 13, 2015 · Ultrasmall superparamagnetic iron oxide nanoparticles (USPIOs) modified with a novel cyclic arginine-glycine-aspartate (RGD) peptide were made and radiolabeled as single-photon emission computed tomography (SPECT) and magnetic resonance imaging (MRI) dual-modality agents for imaging of breast cancer. Nov 7, 2021 · Magnetic resonance imaging contrast of iron oxide nanoparticles developed for hyperthermia is dominated by iron content. MTX loaded magnetic nanoparticle was radiolabeled with technetium-99 m with 89% eciency. In recent years, there has been a greater emphasis on producing nano constructs that may be utilized as core platforms for connecting medicinal radionuclides with various methodologies for molecular imaging and targeted medication administration. Jul 10, 2018 · PDF | In this study, magnetic multimodal nanoparticles with potential applications in magnetic- and nuclear-medicine imaging, magnetic resonance | Find, read and cite all the research you need Radiolabeled iron oxide nanoparticles (RIONs) combine their intrinsic magnetic behavior with the extrinsic character of the radionuclide additive, so that they constitute a platform of multifaceted physical properties. In this paper, amino acid coated and radiolabeled magnetic nanoparticles (MNPs) were prepared as a potential diagnostic agent. Oct 29, 2020 · Abstract Nowadays, emerging radiolabeled nanosystems are revolutionizing medicine in terms of diagnostics, treatment, and theranostics. Radiotracer technology is a powerful tool for biological and Because of their large surface area nanoparticles can be radiolabeled at high specific activity, increasing the sensitivity of detection as well as the payload of therapeutic isotopes. Sep 1, 2019 · Abstract In this paper, amino acid coated and radiolabeled magnetic nanoparticles (MNPs) were prepared as a potential diagnostic agent. 4,5 They can be further decorated with targeting agents such as antibodies (Abs)6-8 and aptamers (Aps)9,10 used for targeted imaging and therapy – an approach the so-called diapeutics/theranostics. 89 MeV is a positron emitting) and investigate the characteristics related to their potential application as a dual-modality PET/MRI imaging agent. Statistically significant decreases in tumor burden were noted for groups treated simultaneously with both active platinum complexes and the application of an external magnetic field versus controls. Aug 26, 2025 · Radiolabeled magnetic nanoparticles (MNPs), particularly superparamagnetic iron oxide nanoparticles (SPIONs), have gained significant attention in the field of cancer theranostics due to their potential in targeted therapy and molecular imaging. Nov 13, 2023 · Iron oxide nanoparticles (IONP) have been hailed as potential game-changers in biomedical imaging owing to their biocompatibility and size-dependent properties. Methods In this work, silica coated magnetic nanoparticles (SiO 2 @MNPs) were synthesized. Apr 4, 2023 · Request PDF | In vitro evaluation of radiolabeled methotrexate loaded magnetic nanoparticle delivery system | Magnetic nanoparticles were synthesized via the chemical co-precipitation method using Quantifying the distribution of nanomaterials in complex samples is of great significance to the toxicological research of nanomaterials as well as their clinical applications. The development of integrated positron emission tomography (PET)/magnetic resonance imaging (MRI) scanners opened a new scenario for cancer diagnosis, treatment, and follow-up. Sep 30, 2016 · Functionalized magnetic and gold NPs (MNPs and GNPs, respectively) have produced the potential of nanoparticles as sensitive multifunctional probes for molecular imaging, photothermal therapy and drug delivery and targeting. Jun 1, 2019 · Request PDF | Bioevaluation of 99mTc (I) Carbonyl-Radiolabeled aminoacid coated magnetic nanoparticles in vivo | In this paper, amino acid coated and radiolabeled magnetic nanoparticles (MNPs Here we present nanoparticles composed of palladium-103 core and iron oxide shell (Figure 1A) that respond to AMF (50-750 kHz, 15-30 mT) with specific power loss up to 225 W/g (Figure 1B), sufficient for thermal ablation of tumors (15 cm3). Austin J Nanomed Nanotechnol 2:10–19 Torres R, Tavare R (2011) Synthesis of 64CuII–bis (dithiocarbamatebisphosphonate) and its conjugation with superparamagnetic iron oxide nanoparticles. The efect of radiolabeled nanoparticles on cells was determined on human cervical cancer (HeLa) and human breast (MCF7) cancer cell lines. Palladium-103 (t1/2=17d), with its low-energy X-rays (21 KeV) derived from the electron capture decay, is well-suited for delivering a radiotherapeutic The development of integrated positron emission tomography (PET)/magnetic resonance imaging (MRI) scanners opened a new scenario for cancer diagnosis, treatment, and follow-up. In this work, silica coated magnetic nanoparticles (SiO2@MNPs) were synthesized. Multimodal imaging combines functional and morphological information Jan 1, 2019 · Of these NHs, radiolabeled nanosystems appear to provide significantly improved clinical outcomes. Significant breakthrough has been made toward the development of various radiolabeled nanoparticles, which can be used as novel cancer diagnostic tools in multimodality imaging systems. Molecular imaging exploits multimodal Oct 1, 2009 · This review summarizes the current state-of-the-art of radiolabeled nanoparticles for molecular imaging and internal radiotherapy applications targeting cancer. Of various nanoparticles, magnetic iron oxide nanoparticles with Functionalized magnetic and gold NPs (MNPs and GNPs, respectively) have produced the potential of nanoparticles as sensitive multifunctional probes for molecular imaging, photothermal therapy and drug delivery and targeting. Guanine (Gua) was conju-gated to the magnetic nanoparticles (MNPs) using glutaraldehyde as a cross-linker. These radionuclides include polymeric nanoparticles (NPs), liposomal carriers, dendrimers, magnetic iron oxide NPs, silica NPs, carbon nanotubes, and inorganic metal-based nanoformulations. Materials and Methods To enable In vivo PET imaging, the GO Aug 1, 2012 · Request PDF | Preparation and characterization of radiolabeled magnetic nanoparticles as an imaging agent | Magnetic nanoparticles were prepared by a reduction–precipitation method and coated Abstract Dual-modality contrast agents (DMCA), such as radiolabeled magnetic nanoparticles, have attracted significant attention in diagnostic applications due to their potency for the timely and accurate diagnosis of diseases. The work presented here focuses on the development and biological application of novel radiolabeled magnetic nanoparticles for multimodal PET/MRI imaging. Glaus Functionalized magnetic and gold NPs (MNPs and GNPs, respectively) have produced the potential of nanoparticles as sensitive multifunctional probes for molecular imaging, photothermal therapy and drug delivery and targeting. Sep 20, 2024 · Consequently, radiolabeled nanoparticles exhibit substantial potential in driving forward the realms of multimodal imaging and theranostic applications. Engle ⊥ , Jimin Liang ‡ , Jie Tian *∥ , and Weibo Cai *§⊥# Jan 24, 2014 · Radiolabeled nanoparticles bearing intrinsic properties have gained great interest in multimodality tumor imaging over the past decade. Magnetic nanoparticles can be radiolabeled with isotopes that are positron emitting for the imaging application. One area where IONP has shown particular promise is magnetic resonance imaging (MRI), which traditionally uses superparamagnetic nanomaterials to produce negative contrast that darkens the tissues where nanoparticles accumulates 10 hours ago · When integrated with magnetic nano-formulations, 177Lu-labeled systems combine the benefits of targeted radiation therapy (TRT) with the unique properties of magnetic nanoparticles (MNPs), such as magnetic resonance imaging (MRI) contrast enhancement and magnetically guided drug delivery to address challenges in diagnosis and treatment of Apr 25, 2022 · Background Recent advances in nanotechnology have offered new hope for cancer detection, prevention, and treatment. Feb 12, 2024 · Purpose Radiolabeled graphene oxide (GO) nanosheets has been one of the most extensively studied nanoplatform for in vivo radioisotope delivery. Capitalizing on the unique physical and functional properties of nanoparticles, radiolabeled nanomaterials or nano-radiopharmaceuticals have the potential to enhance imaging and therapy of human diseases. With the capacity to provide enormous flexibility, radiolabeled nanoparticles have the potential to profoundly impact disease diagnosis and patient management in the near future. Functionalized magnetic and gold NPs (MNPs and GNPs, respectively) have produced the potential of nanoparticles as sensitive multifunctional probes for molecular imaging, photothermal therapy and drug delivery and targeting. Sep 30, 2016 · Functionalized magnetic and gold NPs (MNPs and GNPs, respectively) have produced the potential of nanoparticles as sensitive multifunctional probes for molecular imaging, photothermal therapy and Nov 25, 2022 · Abstract Surface modification of magnetic nanoparticles with poly- l-lysine, proline, and tryptophan was used to design potential theranostic agents for the application in cancer diagnosis and radionuclide-hyperthermia therapy. The68Ga-radiolabeled core–shell DTPA magnetic nanoparticles were gathered mostly in the reticuloendothelial system, and the initial coincidence images and biodistribution results in mice matched each other. One area where IONP has shown particular promise is magnetic resonance imaging (MRI), which traditionally uses superparamagnetic nanomaterials to produce negative contrast that darkens the tissues where nanoparticles accumulates. A radiolabeled folate-mediated solid lipid magnetic nanoparticle system was developed by loading superparamagnetic iron oxide nanoparticles (MNP) and docetaxel (DTX) into the solid lipid nanoparticles as a drug delivery system that will function both in cancer treatment and diagnosis. Jul 31, 2012 · Magnetic nanoparticles were prepared by a reduction–precipitation method and coated with an amino silane coupling agent. Aug 1, 2021 · Radiolabeled magnetic nanoparticles for theranostic application Advancements in synthesis and physicochemical properties such as high surface area, better quantum efficiencies, etc. Aug 26, 2025 · Radiolabeled magnetic nanoparticles (MNPs), particularly superparamagnetic iron oxide nanoparticles (SPIONs), have gained significant attention in the field of cancer theranostics due to their potential in targeted therapy and molecular imaging. Superparamagnetic iron oxide nanoparticles (SPIONs) are the prosperous group of NPs with the capability to apply Synthesis and evaluation of radiolabeled, folic acid-PEG conjugated, amino silane coated magnetic nanoparticles in tumor bearing Balb/C mice Dec 13, 2021 · Quantifying the distribution of nanomaterials in complex samples is of great significance to the toxicological research of nanomaterials as well as their clinical applications. Common techniques (Fourier transform infrared spectroscopy, scanning elec-tron microscopy, X-ray diffraction, and vibrating elec-tronmicroscopy Functionalized magnetic and gold NPs (MNPs and GNPs, respectively) have produced the potential of nanoparticles as sensitive multifunctional probes for molecular imaging, photothermal therapy and drug delivery and targeting. In this preliminary study, the radiochemical purity for the radiolabeled magnetic nanoparticles was examined, and the possibility of the magnetically induced Aug 12, 2023 · Radiolabeled nanoparticles show promising results in metastatic breast and lung cancer, although this field of research needs more clinical studies, mainly on the comparison of nanoparticles with chemotherapy. Between these nano-platforms, polymeric NPs have gained attention in Introduction Functionalized nanoparticles (NPs) with various linkers and functional groups have been developed as carriers for drugs,1-3 genes. Shaghaghi et al. Abstract Nanomaterials offer unique physical, chemical and biological properties of interest for medical imaging and therapy. Guanine (Gua) was conjugated to the magnetic nanoparticles (MNPs) using glutaraldehyde as a cross-linker. Current progress in nanotechnology and nanomedicine has exploited the possibility of designing tumor-targeted nanocarriers able to deliver radionuclide payloads in a selective manner to . By Functionalized magnetic and gold NPs (MNPs and GNPs, respectively) have produced the potential of nanoparticles as sensitive multifunctional probes for molecular imaging, photothermal therapy and drug delivery and targeting. Ehlerding ⊥ , Stephen A. Between these nano-platforms, polymeric NPs have gained attention in Different nanoparticles based multimodal probes have been studied for bone imaging. Jul 4, 2023 · In this study, a radiolabeled folate-mediated solid lipid magnetic nanoparticle (SLMNP) system was developed by loading superparamagnetic iron oxide nanoparticles (MNP) and docetaxel (DTX) into Sep 1, 2019 · Abstract In this paper, amino acid coated and radiolabeled magnetic nanoparticles (MNPs) were prepared as a potential diagnostic agent. Magnetic nanoparticles were synthesized and functionalized by l Jan 27, 2023 · Radiolabeled iron oxide nanoparticles (RIONs) combine their intrinsic magnetic behavior with the extrinsic character of the radionuclide additive, so that they constitute a platform of multifaceted physical properties. M. Semantic Scholar extracted view of "Advances and Challenges in the Application of Radiolabeled Magnetic Nanoparticles for Cancer Theranostics" by Z. Mar 7, 2025 · Superparamagnetic iron-oxide nanoparticles (SPIONs) are promising probes for biomedical imaging, but the heterogeneity of their magnetic properties is difficult to characterize with existing methods. In this study, we describe the preparation and charac-terization of 68Ga radiolabeled core–shell DTPA magnetic nanoparticles (68Ga, t1/2 = 67. Radiotracer technology is a powerful tool for biological and environmental tracing of nanomaterials because it has the This review article focuses on the application of radiolabeled nanoparticles in detecting diseases such as cancer and cardiovascular diseases and also presents an overview about the formulation, stability, and biological properties of the nanoparticles used for diagnostic purposes. Over the last two decades, there has been an increasing effort to translate nanomaterial-based medicinal products (so-called nanomedicines) into clinical practice and, although multiple nanoparticle-based formulations are clinically available, there is still a disparity A R T I C L E I N F O A B S T R A C T Keywords: 99m-technetium tricarbonyl core Magnetic nanoparticles Radiolabeling In vivo In this paper, amino acid coated and radiolabeled magnetic nanoparticles (MNPs) were prepared as a potential diagnostic agent. Structural characterization of MNP-Ala and MNP-Ala-MTX were achieved by nanoparticle characterization techniques. Herein, we describe the functionalization of the surface of GO nanosheets with Fe3O4 magnetic nanoparticles, cysteine amino acid as an interface ligand, and cadmium telluride quantum dots. Recent advancements in material engineering have enabled the development of nanoparticles tailored for various imaging techniques, including magnetic resonance imaging (MRI), computed tomography (CT), positron emission tomography (PET Sep 30, 2016 · Functionalized magnetic and gold NPs (MNPs and GNPs, respectively) have produced the potential of nanoparticles as sensitive multifunctional probes for molecular imaging, photothermal therapy and drug delivery and targeting. Jan 17, 2025 · Over the last few years, a plethora of radiolabeled inorganic nanoparticles have been developed and evaluated for their potential use as probes in positron emission tomography (PET) imaging of a wide variety of cancers. The hemocompatibility of a candidate DMCA with human blood is essential for the investigation of its application in vivo. Nanomedicine, a term for the application of nanotechnology in medical and health fields, uses nanoparticles for several applications such as imaging, diagnostic, targeted cancer therapy, drug and gene delivery, tissue engineering, and theranostics. The probe was tested both in vitro and in vivo to determine its receptor targeting efficacy Nanomaterials represent an innovation in cancer imaging by offering enhanced contrast, improved targeting capabilities, and multifunctional imaging modalities. Yan X, Jinhua Z (2014) Recent development of radiolabeled nanoparticles for PET imaging. Jan 1, 2019 · Of these NHs, radiolabeled nanosystems appear to provide significantly improved clinical outcomes. For this purpose, iron magnetic nanoparticles (Fe3O4) were synthesized, coated with alanine (Ala) and loaded with a folic acid antagonist MTX. Common techniques (Fourier transform infrared spectroscopy, scanning electron microscopy, X-ray diffraction, and vibrating electron microscopy) were used to assess the Abstract Radiolabeled magnetic nanoparticles (MNPs), particularly superparamagnetic iron oxide nanoparticles (SPIONs), have gained significant attention in the field of cancer theranostics due to their potential in targeted therapy and molecular imaging. In this chapter, we will discuss the use of gold nanoparticles (AuNPs), magnetic nanoparticles (MNPs), and their hybrid nanoparticles (Au-MHNPs) as radiolabeled nanoparticles for targeted diagnosis and therapy. Jul 4, 2023 · In this study, a radiolabeled folate-mediated solid lipid magnetic nanoparticle (SLMNP) system was developed by loading superparamagnetic iron oxide nanoparticles (MNP) and docetaxel (DTX) into the solid lipid nanoparticles as a drug delivery system that will function both in cancer treatment and diagnosis. Diferent nanoparticles based multimodal probes have been studied for bone imaging. Nanomedicine, a term for the application of nanotechnology in medical and health fields, uses nanoparticles for several applications such as The development of integrated positron emission tomography (PET)/magnetic resonance imaging (MRI) scanners opened a new scenario for cancer diagnosis, treatment, and follow-up. Apr 25, 2022 · Recent advances in nanotechnology have offered new hope for cancer detection, prevention, and treatment. Jul 7, 2023 · In this study, a radiolabeled folate-mediated solid lipid magnetic nanoparticle (SLMNP) system was developed by loading superparamagnetic iron oxide nanoparticles (MNP) and docetaxel (DTX) into the solid lipid nanoparticles as a drug delivery system that will function both in cancer treatment and diagnosis. Jan 27, 2023 · Radiolabeled iron oxide nanoparticles (RIONs) combine their intrinsic magnetic behavior with the extrinsic character of the radionuclide additive, so that they constitute a platform of multifaceted physical properties. The eect of radiolabeled nanoparticles on cells was determined on human cervical cancer (HeLa) and human breast (MCF7) cancer cell lines. The nanoparticle probes contained crystalline iron oxide cores capable of producing strong MRI contrast. Magnetic nanoparticles were synthesized and functionalized by l -alanine and l -cysteine amino acids in one step. Radiolabeled nanocarriers or nanoparticles can be designed and used for cancer diagnostic and therapeutic purposes when tagged with appropriate radionuclides. Mar 1, 2018 · The magnetic 166 Ho-HolG-Pt nanoparticles were selectively delivered to a lung tumor model using an external magnetic field. The radionuclide 68 Ga represents a cost-effective and ideal PET tracking tool for quantitative and non-invasive evaluation via PET/CT imaging. Consequently, radiolabeled nanoparticles exhibit substantial potential in driving forward the realms of multimodal imaging and theranostic applications. MTX Nov 25, 2022 · Abstract Surface modification of magnetic nanoparticles with poly- l -lysine, proline, and tryptophan was used to design potential theranostic agents for the application in cancer diagnosis and radionuclide-hyperthermia therapy. This review highlights recent advancements in the development of various radiolabeled SPIONs, including those functionalized with polyethylene glycol Functionalized magnetic and gold NPs (MNPs and GNPs, respectively) have produced the potential of nanoparticles as sensitive multifunctional probes for molecular imaging, photothermal therapy and drug delivery and targeting. of magnetic nanoparticles make them appealable nanocarriers for molecular imaging and therapeutic applications. Mentioning: 7 - Ferrite magnetic nanoparticles (Fe3O4or iron (II,III) oxide; 15–25 nm of diameter) were developed. To improve the efficacy of targeted diagnosis and Dec 22, 2015 · Over the last decade, radiolabeled iron oxide nanoparticles have been developed as promising contrast agents for dual-modality positron emission tomography/magnetic resonance imaging (PET/MRI) or sin Functionalized magnetic and gold NPs (MNPs and GNPs, respectively) have produced the potential of nanoparticles as sensitive multifunctional probes for molecular imaging, photothermal therapy and drug delivery and targeting. Methods In this work, silica coated magnetic nanoparticles (SiO2@MNPs) were synthesized. Characterization of bare and functionalized magnetic nanoparticles was performed in detail. Currently, the major challenges facing the research on Jan 25, 2025 · In this paper, we will address the underlying chemical and physics of the biomedical applications of magnetic nanoparticles including radioisotope delivery and a magnetic radiolabeled fluid. Abstract Magnetic nanoparticles were prepared by a reduction–precipitation method and coated with an amino silane coupling agent. Recent advances in nanotechnology have offered new hope for cancer detection, prevention, and treatment. Jul 14, 2025 · Diagnostic imaging: radiolabeled nanoparticles can improve imaging quality in PET and SPECT by enhancing uptake and retention in target tissues [15]. Abstract Magnetic nanoparticles were prepared by a reduction-precipitation method and coated with an amino silane coupling agent. MTX loaded magnetic nanoparticle was radiolabeled with technetium-99 m with 89% eficiency. Tumor accumulation in an appropriate disease model was assessed by ex vivo Tracking of radiolabeled nanoparticles in a mouse model by PET/CT imaging will provide a better understanding of nanoparticle delivery to magnetic implants. This review highlights recent advancements in the development of various radiolabeled SPIONs, including those functionalized with Applications were prepared by coating iron oxide nanoparticles with silica, functionalizing with aminopropyltriethoxy silane and coupling with diethylenetriamine pentaacetic acid ligand (DTPA), Radiolabeling of core–shell–DTPA particles with 68Ga radiometal was carried out through chelation of 68Ga(III) ions by DTPA and was used for positron emission tomography. 71 min, b emitter, Emax-= 1. Results Here, we overview the Sep 20, 2024 · Furthermore, nanoparticles function as a unified nanoplatform for the co-localization of imaging agents and therapeutic payloads, thereby optimizing the efficiency of cancer management strategies. Jul 1, 2020 · Radiolabeled magnetic nanoparticles (MNPs), particularly superparamagnetic iron oxide nanoparticles (SPIONs), have gained significant attention in the field of cancer theranostics due to their ABSTRACT: Iron oxide nanoparticles (IONP) have been hailed as potential game-changers in biomedical imaging owing to their biocompatibility and size-dependent properties. Methods for Theranostics, 2012 Nanomaterials offer new opportunities for cancer diagnosis and treatment. Materials & methods: AGuIX@NODAGA nanoparticles were labeled with 68Ga at high efficiency. Apr 4, 2023 · Magnetic nanoparticles were synthesized via the chemical co-precipitation method using ammonium hydroxide as a precipitating agent. Nanomedicine, a term for the application of nanotechnology in medical and health fields, uses nanoparticles for several applications such as imaging, Jun 18, 2025 · Different nanoparticles based multimodal probes have been studied for bone imaging. In vivo evaluation as dual-modality PET–MRI agent. Targeted therapy: functionalized nanoparticles can deliver therapeutic radiation selectively to tumors, minimizing systemic side effects [16, 17]. Here, we perform wide-field imaging of the stray magnetic fields produced by hundreds of isolated ∼30 nm SPIONs using a magnetic microscope based on nitrogen-vacancy centers in diamond. Sep 7, 2024 · DEVELOPMENT AND ANALYSIS OF RADIOLABELED MAGNETIC NANOPARTICLES FOR POSITRON EMISSION TOMOGRAPHY AND MAGNETIC RESONANCE IMAGING A Dissertation Presented to The Academic Faculty By Charles R. mzj lqn4 jhi21 fs1 key jpqo87 pv yabk zshbwv zy